منابع مشابه
Arginine Metabolism: Enzymology, Nutrition, and Clinical Significance L-Arginine and Atherothrombosis
L-arginine, the principal substrate for endothelial nitric oxide synthase, is oxidized to L-citrulline and nitric oxide. Endothelial dysfunction is associated with decreased bioactive nitric oxide production, an abnormality observed in atherothrombosis. Acute or chronic administration of supplemental L-arginine enhances endothelial nitric oxide production and improves endothelial function in th...
متن کاملL-arginine and thrombosis.
To the Editor: Kapostza et al1 reported that the administration of L-arginine (the precursor of nitric oxide synthesis) after surgery resulted in a highly significant reduction in the frequency of embolic signals after carotid endarterectomy in patients who were already being treated with aspirin and heparin. Patients with carotid artery disease usually suffer from coronary atherosclerosis. The...
متن کاملL-arginine and Alzheimer's disease.
Alzheimer's disease (AD), the most common form of dementia, is characterized by progressive neurodegeneration and loss of cognitive and memory functions. Although the exact causes of AD are still unclear, evidence suggests that atherosclerosis, redox stress, inflammation, neurotransmitter dysregulation, and impaired brain energy metabolism may all be associated with AD pathogenesis. Herein, we ...
متن کاملL-arginine and cardiovascular system.
L-arginine is a basic endogenous amino acid. Its significant metabolic role as the product of ammonia detoxification, the urea cycle metabolite, the precursor of proteins, ornithine, urea and creatinine, and the amino acid involved in the formation of active enzyme centers was very well established. The current interest in this amino acid refers mainly to its close relation with an important si...
متن کاملL-Arginine Monograph
Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2004
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/134.10.2798s